Galectin-3 Knockdown Impairs Survival, Migration, and Immunomodulatory Actions of Mesenchymal Stromal Cells in a Mouse Model of Chagas Disease Cardiomyopathy

<div>Evaluation of Gal-3 knockdown efficiency and characterization of MSC lines. Confocal microscopy images showing Actin-F (green), Gal-3 (red), and nuclei stained with DAPI (blue) in wild-type (a) and Gal-3 knockdown MSC (b). Scale bars = 20 <i>μ</i>m. 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(d) Histograms demonstrating expression of surface marker characteristics of MSC and low expression of hematopoietic markers, analyzed by flow cytometry.</div>

Stem Cells International

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Figure 1

Figure 1: Galectin-3 Knockdown Impairs Survival, Migration, and Immunomodulatory Actions of Mesenchymal Stromal Cells in a Mouse Model of Chagas Disease Cardiomyopathy 

Figure 1 | Galectin-3 Knockdown Impairs Survival, Migration, and Immunomodulatory Actions of Mesenchymal Stromal Cells in a Mouse Model of Chagas Disease Cardiomyopathy 