Galectin-3 Knockdown Impairs Survival, Migration, and Immunomodulatory Actions of Mesenchymal Stromal Cells in a Mouse Model of Chagas Disease Cardiomyopathy

<div>Characterization of MSC lines by differentiation assays. (a) Trilineage differentiation assay performed in MSC lines to generate adipocytes, visualized by Oil red staining, osteocytes, visualized by alizarin red staining, and chondrocytes, visualized by Alcian blue staining, respectively. (b) Angiogenic ability demonstrated by endothelial tube formation assay on Matrigel. MSC-WT = wild-type MSC; MSC-Ctrl = MSC transduced with a nontargeting shRNA vector; MSC-Gal3KD = Gal-3 knockdown MSC. Magnification = 200x.</div>

Stem Cells International

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Figure 2: Galectin-3 Knockdown Impairs Survival, Migration, and Immunomodulatory Actions of Mesenchymal Stromal Cells in a Mouse Model of Chagas Disease Cardiomyopathy 

Figure 2 | Galectin-3 Knockdown Impairs Survival, Migration, and Immunomodulatory Actions of Mesenchymal Stromal Cells in a Mouse Model of Chagas Disease Cardiomyopathy 