Transplantation of Rat Mesenchymal Stem Cells Overexpressing Hypoxia-Inducible Factor 2α Improves Blood Perfusion and Arteriogenesis in a Rat Hindlimb Ischemia Model

Figure 3

Transplantation of rMSCs^HIF-2α increased the number of vessel branches. (a) Representative images of synchrotron radiation microangiography. (b) Angiographic score in the rMSC and rMSC^HIF-2α groups was significantly higher than that in the PBS group. indicates significant difference of the indicated groups versus PBS group, . (c) The number of vessel branches in the rMSC^HIF-2α group was significantly higher than that in the rMSCs and PBS groups. indicates significant difference of the indicated group versus rMSCs and PBS groups, .

(a)

(b)

(c)