Table 1: Mean retinal thickness in rabbit eyes before and following hBM-MSC transplantation.

Total retinaRNFLGCLIPLINLOPLONLRPEORLChoroidSclera

Baseline182.5 ± 0.54 ± 16.8 ± 1.511.6 ± 0.06 ± 0.614 ± 1.361.5 ± 0.812.6 ± 165.8 ± 0.592.7 ± 8.7232 ± 3.2
1 h195.3 ± 3.7 (p0 = 0.07)6 ± 2.5 (p0 = 0.6)7.6 ± 1.9 (p0 = 0.8)11.7 ± 0.7 (p0 = 0.9)6.8 ± 1.2 (p0 = 0.7)15.9 ± 4.4 (p0 = 0.8)64.5 ± 3 (p0 = 0.5)14 ± 0.9 (p0 = 0.5)68.3 ± 0.7 (p0 = 0.3)236.8 ± 15.6 (p0 = 0.006)243.8 ± 11.1 (p0 = 0.5)
10 w166.7 ± 16 (p0 = 0.43, p1 = 0.11)8.9 ± 3.9 (p0 = 0.34, p1 = 0.6)8.3 ± 1.3 (p0 = 0.54, p1 = 0.84)16.4 ± 4.7 (p0 = 0.42, p1 = 0.29)9.2 ± 2.2 (p0 = 0.3, p1 = 0.4)12.5 ± 2.8 (p0 = 0.7, p1 = 0.6)42.1 ± 18 (p0 = 0.4, p1 = 0.2)12.1 ± 0.5 (p0 = 0.7, p1 = 0.2)62.8 ± 1.5 (p0 = 0.2, p1 = 0.07)104.9 ± 13.2 (p0 = 0.5, p1 = 0.009)259.9 ± 1.2 (p0 = 0.2, p1 = 0.7)

Comparison of retinal thickness measurements (in μm) using SD-OCT in rabbit eyes before (baseline), 1 hour (1 h), and 10 weeks (10 w) following hBMSC transplantation. All data are presented as mean ± SE from 4 different areas from 2 (baseline, 10 weeks) or 3 (1 hour) rabbits. Scleral thickness was measured from the outer scleral border to the choroid/sclera interface. Student’s t-test was used to evaluate differences in retinal thickness measurements between baseline and following transplantation (p0) and between 1 hour and 10 weeks (p1) following transplantation. RNFL: retina nerve fiber layer; GCL: ganglion cell layer; IPL: inner plexiform layer; INL: inner nuclear layer; OPL: outer plexiform layer; ONL: outer nuclear layer; RPE: retinal pigment epithelium; ORL: outer retina layer. Total retina was measured from RNFL to ORL.