Endometritis and In Vitro PGE₂ Challenge Modify Properties of Cattle Endometrial Mesenchymal Stem Cells and Their Transcriptomic Profile

Figure 5

Volcano plot showing the distribution of differentially expressed genes in PGE₂+ cells as a function of the selected value. Left panel , right panel (a). Details of differential response of endometrial MSCs to the challenge with PGE₂ (b). Cat whiskers plot representing the distribution of normalized intensity values among the two cell lines (LLPh1 and LLPh3) and the four doses (0, 1, 3, and 10 μM of PGE₂) used. The amplitude of the intensity values is wider for PGE₂-treated cells when compared to control (two right columns). Upper or lower extreme red boxes represent the biggest and smallest values of the data set. Lower extreme, the lowest or smallest value in a set of data. Blue boxes represent the median distribution of intensity values (c).

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