Research Article
Optogenetic Inhibition of Striatal Neuronal Activity Improves the Survival of Transplanted Neural Stem Cells and Neurological Outcomes after Ischemic Stroke in Mice
Figure 6
Striatal neuronal activity affected the vascular density in the penumbra after NSC transplantation. (a) The vascular density in the penumbra examined by staining with CD31, bar = 50 μm. (b) Selected fields for imaging evaluation (indicated by red rectangles). The light-colored area represents brain infarct. (c) The quantitative result of vascular density (PBS = 1.00 ± 0.21, NSC = 1.67 ± 0.28, NSC-E = 1.27 ± 0.22, and NSC-I = 2.10 ± 0.26, ). represents . represents .
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