TNF-α Induced the Enhanced Apoptosis of Mesenchymal Stem Cells in Ankylosing Spondylitis by Overexpressing TRAIL-R2

Figure 1

HDMSCs and ASMSCs shared the same morphology, phenotype, and proliferation capacity. (a) Both HDMSCs and ASMSCs were plastic-adherent and spindle-shaped. (b) Both HDMSCs () and ASMSCs () were positive for CD29, CD44, and CD105 and negative for CD14, CD45, and HLA-DR, suggesting a typical MSC phenotype. (c) The proliferation capacities of HDMSCs () and ASMSCs () were similar when cultured in DMEM with 10% FBS from 1 to 7 days. Optical density (OD) values are presented as the mean ± SD.