Research Article

Inhibition of Lysyl Oxidases Impairs Migration and Angiogenic Properties of Tumor-Associated Pericytes

Figure 2

Activated properties of normal and tumor-associated pericytes. (a) Cell migration was calculated after 6 h in the presence of chemical stimulus, relative to basal cell migration without chemotaxis. (b) Cell proliferation based on BrdU incorporation after 24 h in culture. Kinetics of tube-like formation by (c) normal pericytes and (d) tumor-associated pericytes, under angiogenic conditions in vitro. Normal pericyte samples: NP-Ad and NP-Mu. Tumor-associated pericyte samples: TP-Nbl and TP-Epn. Significance level: , , and .