Combined Analysis of Endothelial, Hematopoietic, and Mesenchymal Stem Cell Compartments Shows Simultaneous but Independent Effects of Age and Heart Disease
Table 1
Baseline characteristics of the study population.
Characteristics
Heart disease
LV dysfunction
IHD ()
VHD ()
Presence ()
Absence ()
Age (years)
61.0 ± 8.5
63.0 ± 8.9
0.977
63 ± 8.7
59 ± 9.4
0.382
Male (n)
15
9
0.236
14
11
0.160
BMI (kg/m2)
26.2 ± 2.8
27.6 ± 8.92
0.015
27 ± 6.3
25 ± 3.1
0.526
Hypertension (%)
94.4
92.9
0.854
88
80
0.357
Smoking (%)
66.7
80
0.222
55
45
0.335
Diabetes (%)
80
86.7
0.605
83
75
0.504
LV EF (%)
55.6 ± 13.7
56.2 ± 13.3
0.749
43 ± 4.3
67 ± 6.5
<0.001
LV mass
110 ± 30.16
131 ± 46.39
0.422
140 ± 26.1
104 ± 22.2
0.045
Hypertrophy (n)
11
12
0.301
13
8
0.673
β-blockers (%)
90
31.3
<0.001
76
63
0.401
Aspirin (%)
90
37.5
<0.001
72
63
0.542
Statins (%)
85
43.8
0.009
82
73
0.615
Hematocrit (%)
38.6 ± 6.6
38.8 ± 4.6
0.910
38 ± 5.8
39.2 ± 5.7
0.693
Hemoglobin (g/dL)
12.7 ± 2.1
12.8 ± 1.6
0.904
12.4 ± 1.9
12.8 ± 1.9
0.793
Leukocytes (×103/μL)
9.6 ± 3.9
13.0 ± 2.3
0.106
7.9 ± 3.1
6.7 ± 2.5
0.544
Glucose (mg/dL)
133.6 ± 36.4
141.8 ± 63.7
0.629
129.8 ± 49.8
138.7 ± 50.1
0.303
Creatinine (mg/dL)
1.0 ± 0.4
1.0 ± 0.3
0.772
1.02 ± 0.4
1.07 ± 0.3
0.665
Sodium (mEq/L)
137.9 ± 3.6
138.8 ± 2.6
0.392
138.5 ± 3.38
138.1 ± 2.99
0.687
Potassium (mEq/L)
4.4 ± 0.5
4.3 ± 0.4
0.600
4.42 ± 0.4
4.31 ± 0.5
0.477
BMI: body mass index; EV: ejection fraction; IHD: ischemic heart disease; LV: left ventricular; VHD: vascular heart disease. The results are presented as mean and standard deviation or median and interquartile range. value, Student’s t-test and chi-square test.
