Evaluating Wharton’s Jelly-Derived Mesenchymal Stem Cell’s Survival, Migration, and Expression of Wound Repair Markers under Conditions of Ischemia-Like Stress

Figure 6

Changes in wound healing related gene expression as evidenced by PCR array. Scatterplot comparing wound healing related gene expression profile between control and ischemic WJ-MSCs. Genes with at least 2-fold differential expression are depicted (a). RT-PCR validation of a few randomly selected genes from the wound healing RT² Profiler PCR Array. PCR was performed using complementary cDNA pooled from three different samples, each of ischemic and their corresponding control WJ-MSC cultures. GAPDH was used as an internal control. TSG6 and SDF1, which were not part of the array, are shown in the box (b).

(a)

(b)