IGF-1 Gene Transfer to Human Synovial MSCs Promotes Their Chondrogenic Differentiation Potential without Induction of the Hypertrophic Phenotype

Figure 2

Gross and DNA-corrected glycosaminoglycan (GAG) content of pellet cultures (in μg). The pellets were analyzed for GAG after 14 days in the differentiation medium using a Blyscan sulfated GAG assay kit. Control values (left) versus IGF-1 gene transfer values (right). (a) Box plot of gross GAG content of the pellet cultures. (b) Box plot of DNA-corrected GAG content. .

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