Selective and Irreversible Induction of Necroptotic Cell Death in Lung Tumorspheres by Short-Term Exposure to Verapamil in Combination with Sorafenib

Figure 6

Chloroquine potentiates VP + SF effects on cell viability. Cells growing under PPSS for 8–10 days were incubated with VP (100 μM) + SF (5 μM) alone or in the presence of 1-M-D-T or CQ for 24 h. Cell viability was measured by the MTT assay. Results (X ± SD) are representative of two independent experiments performed in sextuplicate. indicates (ANOVA).