Stem Cells International / 2017 / Article / Tab 2

Research Article

Predicting the Remaining Lifespan and Cultivation-Related Loss of Osteogenic Capacity of Bone Marrow Multipotential Stromal Cells Applicable across a Broad Donor Age Range

Table 2

Transcript relationships with PD-BS and osteoprogenitor indicators.

GeneCorrelation with PD-BS (rho = ()) Gradient
Range
(min–max)
Also related to PD?Relationship with CFU-O?Relationship with Ca++?

Higher expression closer to senescence
 ACVR2A−0.454−0.07270.07–3.41YYY
 ALPL−0.348−0.10950.03–5.26YY
 ANGPTL4−0.422−0.03360.01–1.57YY
 BAMBI−0.454−0.22790.29–8.67YYY
 BMPER−0.686−0.09850.06–9.28YYY
 COL1A1−0.551−7.27216.35–302YYY
 COL1A2−0.340−10.77114.6–632
 FGFR1−0.453−0.23150.61–13.6YY
 FZD4−0.477−0.07890.07–12.2YY
 IGFBP3−0.417−5.11898.78–236YY
 JAG1−0.465−0.18760.25–27.0Y
 SFRP4−0.511−0.10910.004–35.4YYY
SORT1−0.331−0.15150.134–5.68YY
SPARC−0.753−16.61433.2–545YYY
 TNFRSF11B−0.642−0.72250.179–29.2YYY
Lower expression closer to senescence
 CEBPA0.3580.00120.001–0.119Y
 SFRP10.3690.00340.002–0.634Y
 SOX20.3900.37510.005–22.9Y

; ; Y (yes) = ; empty = no significance. Strongest candidate for prediction model based on multiple correlations and steepest gradient.

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.