BMP4/LIF or RA/Forskolin Suppresses the Proliferation of Neural Stem Cells Derived from Adult Monkey Brain

Figure 6

BMP4/LIF and RA/Forskolin affected the cell morphology. (a) Monkey NSCs were treated in control media or BMP4/LIF or RA/Forskolin factors media for 6 days. (A) Control; (B) BMP4/LIF group; (C) RA/Forskolin groups. The phenotype of single cells in BMP4/LIF and RA/Forskolin groups showed significant changes. (b) The length-width ratio suggested that BMP4/LIF and RA/Forskolin affected the cell morphology and may induce monkey NSC-like cells differentiation. Scale bar = 50 μm. Data represent the mean values ± SD; value < 0.001.

(a)

(b)