The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow

<div>The characteristic of mesenchymal stromal cells derived from amnion (AM-MSCs) and bone marrow (BM-MSCs). (a) The adherent cells exhibited the spindle-shaped morphology and reached 80% confluence at day 14. (b) Immunophenotype of AM-MSCs and BM-MSCs at passage 3. (c) The adipogenic and osteogenic differentiation potential of AM-MSCs and BM-MSCs. The formation of lipid droplet was observed in cytoplasm of AM-MSCs and BM-MSCs after adipogenic induction for 35 and 21 days, respectively. Alizarin red S positive was observed in AM-MSCs and BM-MSCs cultured in osteogenic differentiation medium for 21 and 14 days. Micron bar = 100 <i>μ</i>m.</div>

Stem Cells International

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Figure 1

Figure 1: The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow 

Figure 1 | The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow 