Tumorigenic and Differentiation Potentials of Embryonic Stem Cells Depend on TGF<i>β</i> Family Signaling: Lessons from Teratocarcinoma Cells Stimulated to Differentiate with Retinoic Acid

<div>Proliferative activity and differentiation dynamics of ES R1 and EC F9 cells after 10 days of RA stimulation and 3 days after RA withdrawal. (a) Experimental design of RA-induced differentiation of ES R1 and EC F9 cells. (b and d) Flow cytometric analysis of the distributions of the cell cycle stages in the populations of RA-stimulated ES R1 and EC F9 cells. (c and e) Flow cytometric analysis of the number of Oct4-expressing cells in the populations of RA-stimulated ES R1 and EC F9 cells. The data are represented as the mean ± s.e., ANOVA.</div>

Stem Cells International

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Figure 1: Tumorigenic and Differentiation Potentials of Embryonic Stem Cells Depend on TGF<i>β</i> Family Signaling: Lessons from Teratocarcinoma Cells Stimulated to Differentiate with Retinoic Acid 

Figure 1 | Tumorigenic and Differentiation Potentials of Embryonic Stem Cells Depend on TGFβ Family Signaling: Lessons from Teratocarcinoma Cells Stimulated to Differentiate with Retinoic Acid 