Research Article

Tumorigenic and Differentiation Potentials of Embryonic Stem Cells Depend on TGFβ Family Signaling: Lessons from Teratocarcinoma Cells Stimulated to Differentiate with Retinoic Acid

Figure 2

The gene expression patterns of pluripotency and embryonic lineage markers and TGFβ factors in the course of RA-induced differentiation of ES R1 and EC F9 cells. The gene expression levels of each gene in differentiated cells were evaluated relative to the gene expression levels in undifferentiated ES R1 cells. The data are represented as the mean ± s.d.; significant differences were estimated using ANOVA.