Tumorigenic and Differentiation Potentials of Embryonic Stem Cells Depend on TGF<i>β</i> Family Signaling: Lessons from Teratocarcinoma Cells Stimulated to Differentiate with Retinoic Acid

<div>ALP activity and expression of Oct4 and Gata4 in differentiating ES R1 and EC F9 cells after RA stimulation for 10 days and 3 days after RA withdrawal. Nuclei were counterstained with DAPI. A significant number of the ES R1 and EC F9 cells expressed both Gata4 and Oct4 at all stages of RA-stimulated differentiation. Scale bar = 100 <i>μ</i>m.</div>

Stem Cells International

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Figure 3: Tumorigenic and Differentiation Potentials of Embryonic Stem Cells Depend on TGF<i>β</i> Family Signaling: Lessons from Teratocarcinoma Cells Stimulated to Differentiate with Retinoic Acid 

Figure 3 | Tumorigenic and Differentiation Potentials of Embryonic Stem Cells Depend on TGFβ Family Signaling: Lessons from Teratocarcinoma Cells Stimulated to Differentiate with Retinoic Acid 