Stem Cells International / 2017 / Article / Fig 1

Research Article

Kindlin-2 Modulates the Survival, Differentiation, and Migration of Induced Pluripotent Cell-Derived Mesenchymal Stromal Cells

Figure 1

Kindlin-2 expression pattern, overexpression/knockdown, and targets. (a) mRNA expression levels of Kindlin-2 in F134 iPSCs and different passages of iPSC-MSCs indicated significant differences with BM-MSCs; total proteins were extracted from all cell types. (b) Western blotting was performed using an anti-Kindlin-2 monoclonal antibody. (c) Real-time qPCR was performed to quantify mRNA levels of Kindlin-2 in iPSC-MSCs (passages 1–3) with Kindlin-2 overexpression or knockdown. (d, e) Western blot analysis (d) and densitometry (e) performed with ImageJ software were performed and indicate efficient overexpression and knockdown. Data represents the mean expression values normalized to the housekeeping gene GAPDH. difference . difference .

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.