Research Article

Normal versus Pathological Cardiac Fibroblast-Derived Extracellular Matrix Differentially Modulates Cardiosphere-Derived Cell Paracrine Properties and Commitment

Figure 4

Screening of conditioned media from CG-N and CG-P CDCs for paracrine molecules. (a) Representative blots from protein arrays of CDC-conditioned media. A selection of growth factors, chemokines, and cytokines of interest is highlighted in the panel. Differential analysis of conditioned media from CG-N and CG-P CDCs revealed a distinctive modulation in the secretion profile of a subset of cytokines, as plotted in (b). OD: optical density; CG-N: normal cardiogel; CG-P: pathological cardiogel.
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