Induced Pluripotent Stem Cells Reduce Progression of Experimental Chronic Kidney Disease but Develop Wilms’ Tumors

Figure 2

Immunohistochemistry of renal tissue from 5/6 nephrectomized rats, BMSC and iPS. Immunolocalization of CD68-positive cells; staining for VEGF; expression of TGF-β in the renal cortex. Data are expressed as means ± SD. Representative images of immunolocalization of TGF-β, VEGF, and CD68 cells (macrophages) in the renal cortices of the CKD, BMSC, and iPS groups on postoperative day 60 (magnification: 400x). versus CKD.