Research Article

Induced Pluripotent Stem Cells Reduce Progression of Experimental Chronic Kidney Disease but Develop Wilms’ Tumors

Table 2

Histological changes and the effect of treatment with BMSC and iPS in 5/6 nephrectomized animals.

CKDBMSCiPS

GS23.6 ± 13a4 ± 31.8 ± 1
TID78.2 ± 1543 ± 2962 ± 56

CKD: untreated chronic kidney disease; BMSC: rats treated with mesenchymal stem cells; iPS: rats treated with induced pluripotent stem cells; GS: glomerular sclerosis; TID: tubular damage. Data are expressed as means ± SD (a versus BMSC and iPS).