Induced Pluripotent Stem Cell for the Study and Treatment of Sickle Cell Anemia

Figure 12

Hematoxylin and eosin (HE) staining images of histological sections of iPSC PBscd02 and iPSC PBscd03 teratomas, identifying tissue cells from the 3 germ layers. (I, II, and III) Images showing tissues originating from the mesodermal lineage, such as chondrocytes, adipocytes, osteocytes, and muscle cells, and the endoderm as columnar epithelium, with apparently secretory characteristics. (IV, V) Images identifying tissues originating from the ectodermal lineage as pigmentary epithelium consisting of melanocytes and originating from the mesodermal lineage such as chondrocytes, adipocytes, and osteocytes. Photographs obtained by light-field optical microscopy.