Review Article

Mesenchymal Stem Cells Transplantation following Partial Hepatectomy: A New Concept to Promote Liver Regeneration—Systematic Review of the Literature Focused on Experimental Studies in Rodent Models

Table 3

Advantages and disadvantages of transplantation of ADSCs compared to BM-MSCs and minimal criteria to define MSCs are reported.

BM-MSCs ADSCsMinimal criteria to define MSCS
AdvantagesDisadvantagesAdvantagesDisadvantages

Earliest foundDonor shortedAbundantNRExpression of
CD105+ CD73+ CD90+ 
Lack of expression of:  
CD45−  
CD34−  
CD14− or CD11b−  
CD79a− or CD19−  
HLA-DR (−)

Largest reservedAge relatedLess InvasiveNRAdhesion to plastic in standard culture conditions

Prevalently usedHighly invasiveEasily isolatedNRIn vitro differentiation into osteoblasts, adipocytes and chondroblasts

Easily rejectedImmunosuppressiveNR