Induction of Pluripotent Stem Cells from a Manifesting Carrier of Duchenne Muscular Dystrophy and Characterization of Their X-Inactivation Status

Figure 2

In vivo differentiation of 609-5 iPS cells (XX) and 386S-11 (XXX) iPS cells. Six months after transplantation into the testes of NOD/Scid mice, hiPS cells (609-5: (a–d), 386S-11: (e–h)) had formed teratomas, including mesodermal tissues (adipocytes, cartilage, and muscle), endodermal tissues (mucus-producing epithelium), and ectodermal tissues (neuronal rosette, epidermal cells, and pigmented cells).

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