Vitamin C in Stem Cell Biology: Impact on Extracellular Matrix Homeostasis and Epigenetics

Figure 1

Vitamin C metabolism and activities. Vitamin C, in humans, must be introduced by daily intake through diet. It plays crucial roles both for the proper function of healthy organs and tissues and for tissue repair and regeneration. VitC may act as a scavenger against reactive oxygen species (ROS) and as a chelator, for example, iron metabolism. Both VitC and its catabolic product, dehydroascorbate (DHA), are excreted through urine.