|
| Cell type | Effect of exogenously supplied vitamin C | Concentration | Ref. |
|
| ASCs (adipocyte stem cells) | ↑ Proliferation | 250 μg/ml | [149] |
| hMSCs (human mesenchymal stem cells) | ↑ Proliferation | 50 μg/ml | [143] |
| CPC (cardiac progenitor cells) | ↑ Proliferation | 10–250 μg/ml | [150] |
| ISCs (intestinal stem cells) | ↑ Proliferation/self-renewal | 10–250 μM | [151] |
| Caprine SSCs (spermatogonial stem cells) | ↑ Proliferation | 40 μM | [152] |
| Cord blood-derived MSCs (mesenchymal stem cells) | ↓ Proliferation | 500 μM | [163] |
| TBV2 ESCs | ↑ Naive state of plurypotency | 50–150 μg/ml | [1] |
| ESCs | ↑ Naive state of plurypotency | 10–500 mM | [3] |
| Ovarian follicles | ↑ Survival | 50 μg/ml | [182] |
| Porcine oocytes | ↑ Maturation | 50 μg/ml | [181] |
| J1 ESCs | ↑ Pluripotency marker expression | 50 μg/ml | [154] |
| Periodontal ligament stem cells (PDLSCs) | ↑ Telomerase activity | 20–50 μg/ml | [156] |
| Bone marrow-derived MSCs (mesenchymal stem cells) | ↑ Osteoblastic differentiation | 50 μg/ml | [162] |
| Cord blood-derived MSCs (mesenchymal stem cells) | ↑ Osteogenesis | 250 μM | [163] |
| ESCs | ↑ Osteoclastogenesis | 50 μg/ml | [145] |
| hMSCs (human mesenchymal stem cells) | ↑ Tenogenesis | 50 μg/ml | [93] |
| E14 ESCs | ↑ Adipocyte differentiation | 25 μg/ml | [165] |
| C6R8 mESCs | ↑ Cardiogenesis | 10–100 μM | [170] |
| Fgfr1−⁄− R1 mESCs | ↑ Rescue of cardiomyocyte differentiation | 10 μM | [171] |
| iPSCs | ↑ Cardiogenesis | 10–250 μg/ml | [150] |
| HaCaT cells | ↑ Epidermal keratinocyte differentiation | 1 mM | [141] |
| Bone marrow-derived MSCs (mesenchymal stem cells) | ↑ Smooth muscle cell differentiation (SMCs) | 30 μM | [169]; [168] |
| Mesencephalic precursor cells | ↑ Dopaminergic neuron differentiation | 100 μM | [167]; [166] |
| Pre-iPSCs from MEF | ↑ Reprogramming | 25–50 μg/ml | [2] |
| B-cells | ↑ Reprogramming | 50 ng/ml | [125] |
| Porcine somatic cells | ↑ Reprogramming | 50 μg/ml | [179] |
| MEFs | ↑ Reprogramming | 25–50 μg/ml | [131] |
|
