Obesity Enhances the Conversion of Adipose-Derived Stromal/Stem Cells into Carcinoma-Associated Fibroblast Leading to Cancer Cell Proliferation and Progression to an Invasive Phenotype

<div>Serial coculture with obASCs enhances invasive phenotype of breast cancer cells. MCF7 cells were serially passaged or serially cocultured with lnASCs or obASCs and assessed morphologically. Arrowheads indicate more mesenchymal-like phenotype. Scale bar represents 200 <i>μ</i>m.</div>

Stem Cells International

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Figure 6

Figure 6: Obesity Enhances the Conversion of Adipose-Derived Stromal/Stem Cells into Carcinoma-Associated Fibroblast Leading to Cancer Cell Proliferation and Progression to an Invasive Phenotype 

Figure 6 | Obesity Enhances the Conversion of Adipose-Derived Stromal/Stem Cells into Carcinoma-Associated Fibroblast Leading to Cancer Cell Proliferation and Progression to an Invasive Phenotype 