Microarray Analysis Reveals a Potential Role of lncRNA Expression in 3,4-Benzopyrene/Angiotensin II-Activated Macrophage in Abdominal Aortic Aneurysm

Figure 1

Ang II-induced macrophage infiltration and expression of MMP-9 and TNF-α were prominently increased in mice receiving coadministration of Bap. Abdominal aortic tissues were harvested, and transversal sections were prepared. (a) Representative photomicrographs of CD68⁺ cell staining in suprarenal aortic sections: immunoreactivity was visualized using an Alexa Fluor 488 secondary antibody (green). (b) Representative immunohistochemistry staining of TNF-α and MMP-9 in the abdominal aorta from control animals and animals treated with Ang II, Bap, or Ang II/Bap. (c–e) For quantitative analysis of the result. versus control; ^# versus Bap or Ang II group.

(a)

(b)

(c)

(d)

(e)