Cardiac Stem Cells in the Postnatal Heart: Lessons from Development

Figure 1

Summary of mouse heart development. (a) E3.5 preimplantation blastocyst stage showing pluripotent inner cell mass (ICM); (b) E6.5-gastrulating embryo showing mesoderm formation (arrows); (c) at E7.5, myocardial progenitor cells migrate to form the cardiac crescent; (d) at E8, the cardiac crescent fuses at the midline to form the early cardiac tube; (e) at E8.5, the cardiac tube forms a loop; (f) at E12.5–E15.5: the chambers undergo septation.

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