Review Article

Potential Roles of Dental Pulp Stem Cells in Neural Regeneration and Repair

Figure 3

Tissue-engineered constructs of DPSCs, scaffolds, and growth factors and their applications in nervous system diseases. In the constructs, scaffolds can provide biomimetic environments and structural support for cell survival and proliferation. Growth factors can promote neuronal cell proliferation and survival in vivo and in vitro. DPSCs can enhance neuronal regeneration and repair due to their neuronal differentiation potential and their neurotrophic, neuroprotective, angiogenic, and immunomodulatory properties.