Effects of Transplanted Heparin-Poloxamer Hydrogel Combining Dental Pulp Stem Cells and bFGF on Spinal Cord Injury Repair
The analyses of MRI, histology evaluation, and immunohistochemistry. (a) MRI images of HP-bFGF, HP-DPSC, and HP-bFGF-DPSC groups at day 28, and SCI modeling stage at 6 hours. Arrows indicated the segmental SCI. Scale bar: 1 cm. (b) Representative images of HE staining at day 28. Scale bar: 500 μm (4×) and 100 μm (20×). (c) Quantification of the number of ventral motor neurons (VMNs) and the percent of preserved tissue in the gray matter of spinal cord. (d) Representative images of GAP43 from immunohistochemisty. Scale bar: 50 μm. (e) Quantification of the GAP43 positive staining ratio to normal in spinal cord. The quantification results obtained by Image J. Data were presented as mean ± standard error from 3 rats in each group. versus sham group; , versus HP-bFGF group; versus HP-DPSC group.
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