Decreased Count and Dysfunction of Circulating EPCs in Postmenopausal Hypercholesterolemic Females via Reducing NO Production
Table 1
Clinical and biochemical characteristics.
Characteristics
Normocholesterolemic females ()
Hypercholesterolemic females ()
Normocholesterolemic males ()
Hypercholesterolemic males ()
Age (years)
55.1 ± 2.5
56.2 ± 3.0
56.9 ± 3.3
54.9 ± 2.7
Height (cm)
162.4 ± 5.0
162.1 ± 6.1
168.5 ± 6.5#
167.8 ± 6.5#
Weight (kg)
61.9 ± 4.0
63.3 ± 5.4
66.6 ± 5.9#
67.4 ± 4.7#
BMI (kg/cm2)
23.5 ± 1.4
24.1 ± 2.0
23.4 ± 1.2
23.9 ± 1.4
SBP (mmHg)
126.9 ± 9.7
123.5 ± 9.7
128.3 ± 5.7
124.6 ± 7.7
DBP (mmHg)
79.4 ± 8.0
76.7 ± 6.7
80.9 ± 4.9
78.3 ± 6.4
HR (beats/min)
76.9 ± 9.2
75.4 ± 8.2
74.3 ± 9.0
77.4 ± 9.8
AST (mmol/L)
22.0 ± 5.5
22.7 ± 4.9
23.5 ± 4.3
22.1 ± 5.4
ALT (mmol/L)
19.7 ± 5.5
21.3 ± 4.8
21.4 ± 7.5
20.6 ± 5.8
BUN (mmol/L)
4.6 ± 0.9
4.4 ± 0.6
4.7 ± 0.7
4.5 ± 0.7
Cr (mmol/L)
53.3 ± 8.5
51.3 ± 11.9
56.8 ± 9.7
50.6 ± 9.0
LDL (mmol/L)
2.68 ± 0.33
4.20 ± 0.44☆
2.71 ± 0.32
4.30 ± 0.52☆
TC (mmol/L)
4.50 ± 0.48
6.06 ± 0.46☆
4.51 ± 0.40
6.21 ± 0.40☆
HDL (mmol/L)
1.31 ± 0.17
1.25 ± 0.12
1.28 ± 0.17
1.26 ± 0.16
TG (mmol/L)
1.49 ± 0.14
1.55 ± 0.10
1.51 ± 0.13
1.53 ± 0.12
FPG (mmol/L)
4.80 ± 0.47
4.62 ± 0.56
4.82 ± 0.47
4.71 ± 0.44
FMD (%)
7.65 ± 1.51
5.02 ± 1.10☆
7.44 ± 1.78
4.69 ± 1.35☆
BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; HR: heart rate; AST: aspartate transaminase; ALT: alanine aminotransferase; BUN: blood urea nitrogen; Cr: creatinine; LDL: low-density lipoprotein; TC: total cholesterol; HDL: high-density lipoprotein; TG: triglyceride; FPG: fasting plasma glucose; FMD: flow-mediated dilatation. Data are given as mean ± SD. versus normotension in the same sex group; versus postmenopausal females.
