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Aim of the research work | Type of experiment | Main finding(s) | Reference |
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Using BM-MSCs for maxillary sinus floor elevation and bone formation | In vitro | The differentiation of BM-MSCs into osteoblasts was significantly increased, and also, formation of new bone was enhanced after implantation of BM-MSCs during maxillary sinus floor elevation. | [15] |
The usefulness of MSCs and the BMAC with BBM for sinus augmentation | In vivo (on 16 sheep) | New bone formation due to BBM and MSC application | [24] |
Renewal of maxillary sinus deficiencies the using stem cells | On 30 human participants | Higher density of the engineered bone in patients that received stem cells Enriched CD90+ populations are harmless for maxillary sinus floor rebuilding, and they can also be used to accelerate and improve tissue-engineered bone quality. | [16] |
Testing the potential of different stem cell sources about maxillary sinus augmentation | In vivo (6 beagles) | The tissue-engineered bone complexes might be a worthy choice for augmentation of the maxillary sinus in edentulous patients because seeding of PDLSCs or BM-MSCs onto Bio-Oss can encourage bone formation and mineralization. | [13] |
Gabapentin-lactam (GBP-L) in enhancing new bone formation | In vivo (10 adult sheep) | The osteogenic potency of the MSCs and new bone formation in tight contact with the original bone | [25] |
Sinus lifting using bovine bone mineral and autogenous bone marrow concentrate or autogenous bone | In 12 edentulous patients | No implants failed on the control side during osseointegration. No clinically related alterations concerning soft tissue parameters or peri-implant bone loss after one year | [17] |
The bone formation capacity of ADSCs and BMSCs | In a canine sinus floor augmentation model | More proliferative ability as well as larger osteogenic differentiation potential for BMSCs Promoted fast and larger bone regeneration for BMSCs | [14] |
The bone regenerative property of the amniotic epithelial cells (AECs) (an emerging source of progenitor cells) loaded on calcium phosphate | In vivo (in six adult sheep) | Allotransplanted AECs influenced positively on scaffold integration and bone deposition A decreased fibrotic reaction and a restricted inflammatory response as well as an improved angiogenesis Direct participation in bone deposition related to oAEC entrapment within osteoid matrix | [11] |
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