Research Article
MicroRNA-132, Delivered by Mesenchymal Stem Cell-Derived Exosomes, Promote Angiogenesis in Myocardial Infarction
Figure 3
miR-132-electroporated exosomes promoted angiogenesis in vitro and in vivo. (a) Tube formation assay on Matrigel was assessed 6 h after seeding HUVECs pretreated with blank, miR-132 mimic-electroporated or miR-132 inhibitor-electroporated exosomes. Scale bar: 500 μm. (b, c) Quantitative assessment of the total number of meshes and tube length (). , . (d) Gross look of Matrigel plugs. (e, f) Immunofluorescence staining of vessels in the sections of Matrigel plugs and quantitative assessment of capillaries per high-power field in each group (). , .
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