Use of Self-Assembling Peptides to Enhance Stem Cell Function for Therapeutic Angiogenesis

<div>Quantification of angiogenesis from immunohistochemical staining for MSCs, RADA, MSCs + RADA, and control. The markers (a) CD31, (b) vWF, and (c) <i>α</i>-SMA were used to determine angiogenesis and the overall results demonstrate an increase in marker expression in the 3 groups with respect to control, while the MSC + RADA combination group tended to show an overall higher expression compared to MSCs or RADA alone. <svg height="15.2035pt" id="M21" style="vertical-align:-3.429399pt" version="1.1" viewbox="-0.0498162 -11.7741 49.6552 15.2035" width="49.6552pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M278 -108C276 -72 276 -41 276 6C276 132 289 239 307 279C282 327 275 360 273 404C334 402 369 393 402 372C420 379 445 401 457 422C445 442 420 464 402 471C369 449 334 441 273 439C276 506 281 532 311 583C297 609 275 635 252 647C231 635 207 609 194 583C223 532 229 506 232 439C171 442 135 450 103 471C84 463 60 441 49 422C60 401 84 379 103 372C135 393 171 402 232 404C230 360 224 327 199 279C217 239 228 132 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Stem Cells International

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Figure 3

Figure 3: Use of Self-Assembling Peptides to Enhance Stem Cell Function for Therapeutic Angiogenesis 