Review Article
The Roles of Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 in Cancer and Cancer Stem Cells
Table 1
Known target mRNAs of IGF2BP2.
| Target | Effect on translation | Physiological function | Reference |
| IGF2 | Enhancement | Growth, metabolism | [9, 49] | UCP | Inhibition | Metabolism | [12] | PINCH2 | Enhancement | Glomerular stability | [10] | PINCH2 | Inhibition | Cell migration and adhesion | [11] | MURF3 | Enhancement | Myoblast microtubule stability | [11] | CI/CIV | Enhancement | Myoblast microtubule stability | [17] | NRAS | Enhancement | Rhabdomyosarcoma | [147] | HMGA1 | Enhancement | Cell proliferation | [88] |
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