Osteogenic Potential of Human Umbilical Cord Mesenchymal Stem Cells on Coralline Hydroxyapatite/Calcium Carbonate Microparticles

Figure 2

Bright field images of organoids with UCM (A) and BM (B) MSCs during the process of osteogenesis. Images were taken on days 1 (A1, B1), 7 (A2, B2), 14 (A3, B3), and 21 (A4, B4) of the differentiation process and compared to a control (α-MEM) image at day 21 (A5, B5). BM MSCs were observed to proliferate into the voids created by the numerous coral particles by day 7 and UCM MSCs by day 7 (white arrows). SP: scaffold particle. Scale bars: 250 μm.