Intraspinal Transplantation of the Adipose Tissue-Derived Regenerative Cells in Amyotrophic Lateral Sclerosis in Accordance with the Current Experts’ Recommendations: Choosing Optimal Monitoring Tools

<div>Cytokine and chemokine level in CSF after ADRC application. (a) Membrane-based antibody arrays for the parallel determination of the relative levels of human cytokines and chemokines from CSF of ALS patients (resp. P1, P2, and P3). (b) Comparison of TNF<i>α</i>, IFN-<i>γ</i>, IL-1<i>β</i>, IL-6, bFGF, and MMP-9 level after MSC transplantation ( black graph bars—3 months after ADRC application, grey bars—24 hours after cell application). (c) Quantification of CFU frequency. ADRCs obtained after enzymatic isolation were analyzed to evaluate the stem cell/clonogenic population among a heterogeneous stromal cell population.</div>

Stem Cells International

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Figure 2: Intraspinal Transplantation of the Adipose Tissue-Derived Regenerative Cells in Amyotrophic Lateral Sclerosis in Accordance with the Current Experts’ Recommendations: Choosing Optimal Monitoring Tools 

Figure 2 | Intraspinal Transplantation of the Adipose Tissue-Derived Regenerative Cells in Amyotrophic Lateral Sclerosis in Accordance with the Current Experts’ Recommendations: Choosing Optimal Monitoring Tools 