Skin-Derived Stem Cells for Wound Treatment Using Cultured Epidermal Autografts: Clinical Applications and Challenges

Table 1

Comparison between epi-SC- and hf-SC-derived CEAs.

Aspect	epi-SCs	hf-SCs	References
Reported donor age	0 to 59 years	63 to 91 years	[22, 65, 80]
Cultivation period	3 to 4 weeks	4 weeks	[25, 66, 81]
Material required	Skin biopsy (3 cm^2)	40 to 350 anagen hair follicles	[28, 66, 82]
CEA surface	0.8 cm^2 single-CEA surface or larger up to 1.9 m^2 in total can be generated for one patient	0.8 cm^2 single-CEA surface	[17, 22, 23]
Engraftment rate	70%, high variability	80 to 90%	[18, 19, 82]