Downregulated GTCPH I/BH4 Pathway and Decreased Function of Circulating Endothelial Progenitor Cells and Their Relationship with Endothelial Dysfunction in Overweight Postmenopausal Women
Table 1
Clinical and biochemical characteristics.
Characteristics
Normal weight women ()
Overweight women ()
Normal weight men ()
Overweight men ()
Age (years)
56.1 ± 4.7
57.3 ± 4.5
56.7 ± 4.4
55.3 ± 4.1
Height (cm)
163.6 ± 5.6
162.6 ± 6.2
169.3 ± 6.3#
167.8 ± 5.0
Weight (kg)
57.7 ± 4.2
70.0 ± 5.6
63.0 ± 6.5#
74.7 ± 4.5
BMI (kg/cm2)
21.6 ± 1.6
26.5 ± 1.8
21.9 ± 1.4
26.6 ± 2.3
Systolic blood pressure (mmHg)
119.4 ± 9.5
120.9 ± 5.9
121.3 ± 6.6
123.3 ± 9.2
Diastolic blood pressure (mmHg)
73.2 ± 6.8
75.0 ± 5.2
74.7 ± 6.3
76.5 ± 6.9
Heart rate (beats/min)
74.8 ± 8.7
75.9 ± 8.5
73.6 ± 8.6
76.6 ± 8.0
AST (mmol/L)
25.0 ± 6.9
26.6 ± 6.3
28.4 ± 4.0
26.3 ± 5.1
ALT (mmol/L)
21.5 ± 5.7
23.5 ± 4.7
24.78 ± 5.6
24.1 ± 6.1
BUN (mmol/L)
5.4 ± 0.7
5.5 ± 0.9
5.1 ± 0.9
5.3 ± 0.7
Cr (mmol/L)
69.1 ± 12.7
71.4 ± 11.6
66.3 ± 14.3
68.1 ± 13.7
LDL (mmol/L)
2.62 ± 0.39
2.76 ± 0.39
2.56 ± 0.46
2.71 ± 0.42
TC (mmol/L)
4.38 ± 0.53
4.54 ± 0.56
4.23 ± 0.63
4.48 ± 0.58
HDL (mmol/L)
1.33 ± 0.20
1.27 ± 0.13
1.29 ± 0.14
1.23 ± 0.12
TG (mmol/L)
1.58 ± 0.19
1.67 ± 0.20
1.63 ± 0.17
1.69 ± 0.16
FPG (mmol/L)
4.34 ± 0.46
4.68 ± 0.56
4.76 ± 0.50
4.54 ± 0.48
Estradiol (pmol/L)
106.0 ± 26.2
116.5 ± 37.0
102.5 ± 20.1
108.1 ± 19.9
FMD (%)
8.72 ± 1.41
7.08 ± 1.26
8.41 ± 1.24
6.77 ± 1.1
Note: data are given as mean ± SD. BMI: body mass index; AST: aspartate amino transferase; ALT: alanine transaminase; BUN: blood urea nitrogen; Cr: serum creatinine; LDL: low-density lipoprotein; TC: total cholesterol; HDL: high-density lipoprotein; TG: triglyceride; FPG: fasting plasma glucose; FMD: flow-mediated brachial artery dilatation. versus normal weight; versus premenopausal women.
