Review Article

Intraparenchymal Neural Stem/Progenitor Cell Transplantation for Ischemic Stroke Animals: A Meta-Analysis and Systematic Review

Table 2

Effect sizes for cellular treatment effects.

Treatment effectsEffect size95% CITreatment arms

Apoptosis inhibition3.091.94–4.2513
Immunomodulation1.470.34–2.6113
Growth factors (BDNF)1.370.57–2.1714
Growth factors (VEGF)1.150.47–1.8413
Angiogenesis1.180.42–1.9411
Neurogenesis1.230.40–2.0713
Gliosis reduction2.350.22–4.495
White matter function1.000.40–1.613
Enzyme supplementation0.81−0.36–1.976
Axonal function2.471.36–3.571