Research Article

Significance of Glioma Stem-Like Cells in the Tumor Periphery That Express High Levels of CD44 in Tumor Invasion, Early Progression, and Poor Prognosis in Glioblastoma

Figure 5

Invasive and migratory activities of cultured SFCs and PCs and inhibitory effect of CD44 knockdown with CD44 siRNA on their activities. In both invasion (a) and migration (b), cultured SFCs (SFC-1 and SFC-2) showed much higher activity than each PCs (PC-1 and PC-2). These high activities of invasion and migration of SFCs were significantly inhibited by knockdown of CD44 with the siRNA. and .
(a)
(b)