Significance of Glioma Stem-Like Cells in the Tumor Periphery That Express High Levels of CD44 in Tumor Invasion, Early Progression, and Poor Prognosis in Glioblastoma

Figure 7

Representative combined images of MRI and PET-computed tomography for four groups of features with different intensities representing invasion and proliferation in the tumor periphery. Inv: invasion, prol: proliferation, CN: central necrosis. In all images, the upper left is T1-Gd, the upper right is a fluid-attenuated inversion recovery image, and the lower image is Met-PET. Values at the bottom are the mean ± SD of the P/C ratio for CD44 expression (upper row) and the Ki-67 SI in the tumor periphery (lower row). : number of patients.