Noncoding RNA Transcripts during Differentiation of Induced Pluripotent Stem Cells into Hepatocytes

Figure 6

Volcano plots of miRNA expression in HLCs at day 20 and day 24 of differentiation and mature hepatocytes. The plots represent miRNA expression profiles of (a) HLCs at day 20 versus HLCs at day 24, (b) HLCs at day 20 versus hepatocytes, and (c) HLCs at day 24 versus hepatocytes; the x-axis indicates the difference of expression level on a log2 scale, while the y-axis represents corresponding adjusted values (FDR) on a negative log10 scale; statistically significant differences extend vertically; red points indicate genes with significance level of FDR < 0.001; labels are given for the most significant differentially expressed miRNAs.

(a)

(b)

(c)