Ion Channel Expression and Characterization in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Figure 3

Ion channel and receptor expression in hiPSC-CMs. Relative mRNA levels (normalized with GAPDH) of different ion channels and adrenoceptors as well as of muscarinic receptors were analyzed by qPCR in hiPSC-CMs. (a) Mean values of relative mRNA expression of ion channels and receptors in cells from donor 1 (D1) 30 to 40 days (days 30–40) and 50 to 60 day (days 50–60) after the onset of differentiation. (b) Mean values of relative mRNA expression of ion channels and receptors in cells from donor 2 (D2) 30 to 40 days (days 30–40) and 50 to 60 days (days 50–60) after the onset of differentiation. (c) Mean values of relative mRNA expression of ion channels in cells from donor 1 (D1) and donor 2 (D2) 30 to 40 days after the onset of differentiation. (d) Mean values of relative mRNA expression of ion channels in cells from donor 1 (D1) and donor 2 (D2) 50 to 60 days after the onset of differentiation. Results shown are mean ± SEM.