Research Article
Human Umbilical Cord MSC-Derived Exosomes Suppress the Development of CCl4-Induced Liver Injury through Antioxidant Effect
Figure 4
hucMSC-Ex reduced oxidative stress in acute liver injury. (a, b) Immunohistochemistry staining of 8-OHdG and activated caspase 3 in mouse livers. Reduced production of oxidative stress marker 8-OHdG and activated caspase 3 expression was detected in the hucMSC-Ex group (; , ). Original magnification 200x. (c, d) Immunohistochemistry staining of Bax and TUNEL in mouse liver slides. Bax expression and cell apoptosis were decreased in the hucMSC-Ex group (; ). Original magnification 200x.
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