Guanylate-Binding Protein 1 Promotes Migration and Invasion of Human Periodontal Ligament Stem Cells

Figure 1

IFN-γ promoted migration and invasion and expression of GBP1 in PDLSCs. Results of wound healing assay revealed an increase in migration distance of PDLSCs in response to IFN-γ treatment at 1 and 10 ng/ml (a and b). Bar indicates 500 μm in (a). Results of transwell assay showed an increase in invade cell number of PDLSCs in response to IFN-γ treatment at 1 and 10 ng/ml (c and d). Bar indicates 100 μm in (c). GBP1 expression was upregulated in IFN-γ-treated PDLSCs as determined by RT-qPCR (e). ; .

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