Human Bone Marrow Contains Mesenchymal Stromal Stem Cells That Differentiate In Vitro into Contractile Myofibroblasts Controlling T Lymphocyte Proliferation

Table 2

Contraction and relaxation parameters of the membranes.

(a) Contraction

	Tetanus			KCL
	No MSC; ()	MSC; ()		No MSC; ()	MSC; ()
ΔLmax (%)			<0.001			<0.05
Active tension (mN/mm^2)			<0.001			<0.05

(b) Relaxation

	ISDN; ()	BDM; ()
Max Vr (mm/s)			0.35
Isot. relax. time (s)			0.98
−Max dF (mN/s)			0.64
Isom. relax. time (s)			0.45

(a) Maximum amplitude of isotonic shortening (ΔLmax) and values comparing membranes with and without MSC exposed to either tetanus or KCl are shown. (b) Maximum relaxation velocity (Max Vr), time to isotonic relaxation (Isot. relax. time), negative peak of isometric relaxation (−max dF), and time to isometric relaxation (Isom. relax. time) are shown. No significant statistical differences were observed between ISDN and BDM for the 4 parameters of relaxation. () refers to the number of duplicates undertaken.