Guiding the Differentiation Direction of Pancreatic Islet-Derived Stem Cells by Glycated Collagen

Figure 5

Endocrine differentiation of stem cells on modified collagens. After 28 days of differentiation, the differentiation was assessed by immune staining against insulin. With respect to the cells on the uncoated (a) and collagen coated (b; unmodified) surfaces, the differentiation was more efficient in the cells cultured on the Col-M (d), Col-A (e), and Col-R (f). However, Col-G (c) suppressed the endocrine differentiation in PI-MSCs. Scale bar: 50 μm.

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